Tauroursodeoxycholic acid (TUDCA, CAS: 14605-22-2) is the taurine conjugate of ursodeoxycholic acid (UDCA), with the chemical formula C₂₆H₄₅NO₆S and molecular weight 499.70 g/mol. As an endogenous bile acid derivative, its water solubility is 10 times higher than UDCA (>500 mg/mL). The FDA granted it orphan drug designation for amyotrophic lateral sclerosis (ALS) treatment in 2022. The 2023 European Academy of Neurology (EAN) guidelines recommend it as adjunctive therapy for neurodegenerative diseases (Evidence Level: Ⅱa).
Product Name: Tauroursodeoxycholic acid
CAS No.: 14605-22-2
Molecular Formula: C₂₆H₄₅NO₆S