High-grade active substances certified for diagnostic and synthesis applications across European laboratories.
Bile acids, primarily synthesized in the liver from cholesterol, are no longer viewed merely as physiological detergents facilitating lipid digestion. Today, they represent a highly sophisticated class of signaling molecules acting via nuclear receptors such as the Farnesoid X Receptor (FXR) and G-protein coupled receptors like TGR5. In the French biopharmaceutical sector—centered around prominent hubs in Lyon, Paris, and Marseille—cholic acid derivatives have emerged as key structures for metabolic, immunological, and organ-targeted therapies.
As Europe experiences a transition toward complex hepatobiliary drug research, French laboratories and contract development organizations (CDMOs) require highly consistent chemical profiles for Cholic Acid (CA), Chenodeoxycholic Acid (CDCA), and Ursodeoxycholic Acid (UDCA). France’s pharmaceutical landscape demands structural purity that guarantees no cross-contamination of animal pathogens, bringing regulatory pathways like CEP/EDQM certifications to the forefront of sourcing priorities.
The benchmark standard for bile acid APIs utilized in human clinical phases in the EU.
Mandatory registration for bulk chemical supplies imported into the French Territory.
Critical for streamlined marketing authorizations within the French ANSM frameworks.
Integrating innovative research, high-yield extraction, and modern GMP-compliant synthesis routes.
Driven by the strict concept of modern biosafety and health needs, our biological extracts have become the core raw materials for pharmaceuticals, diagnostic reagents, and high-performance health supplements. Our modern separation methodologies achieve optimal purity without sacrificing target molecule bioactivity.
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Leveraging advanced molecular engineering and enzymatic synthesis capabilities, we provide one-stop contract manufacturing services. Our facilities support scaling from initial lab pilot batches to multi-ton commercial production runs with custom specifications.
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The global cholic acid market is closely linked to the livestock industry. High-quality crude ox bile must be sourced from regions with robust animal health controls to prevent bovine spongiform encephalopathy (BSE) and other zoonotic concerns. Our upstream supply network is fully traceable, securing raw materials under stringent biosafety protocols.
Refining crude bile into pure pharmaceutical intermediates requires precise organic solvent crystallization or enzymatic bioconversion. Utilizing modern separation technologies, we remove impurities such as heavy metals, residual proteins, and organic solvents, producing API-grade cholic acid derivatives with consistent physical properties.
To serve the French market, we have established optimized supply chains to navigate customs and REACH procedures smoothly. Complete regulatory documentation (DMF, CEP, CoA, SDS) is prepared for each shipment, minimizing delivery times to research institutes, CDMOs, and manufacturing centers across France.
High-demand functional raw materials for integration into health, nutritional, and metabolic formulas.
Premium energy formulation active ingredient.
Standardized ginsenosides for vitality support.
High concentration of phenylethanoid glycosides.
High purity Icariin content options.
Chengdu Chenlv Herb Co., Ltd. (known as "Chenlv Herb") is a high-tech enterprise specializing in the R&D, manufacturing, and distribution of high-purity botanical extracts, active pharmaceutical ingredients (APIs), and bile acid derivatives.
With our modern manufacturing facility stretching over 9,514 m², we are equipped with extraction, crystallization, and chromatography systems designed to meet international standards. We supply industries worldwide, including pharmaceuticals, dietary supplements, clinical research, and veterinary medicine, with a strong focus on regulatory compliance and reliability.
Connect with Our R&D TeamTailored biochemical solutions matching strict local application requirements.
Serving as key precursors for synthesizing therapeutic agents like Ursodeoxycholic Acid (UDCA) and Obeticholic Acid, targeted at treating primary biliary cholangitis (PBC) and metabolic liver disorders.
Integrated into *in vitro* diagnostic (IVD) kits, utilizing high-grade bile acids and cholesterol substrates as reagents to measure enzymatic activities and serum lipid profiles in clinical laboratories.
Using high-purity Deoxycholic Acid (DCA) and its sodium salts as key active components in localized fat-reduction formulas, manufactured under strict chemical safety standards.
Formulated as bio-equivalent feed additives for livestock and aquaculture, helping to optimize fat digestion, support liver function, and improve feed efficiency metrics.
Why leading French pharmaceutical and industrial buyers partner with Chenlv Herb.
Each batch is analyzed using advanced HPLC, GC-MS, and ICP-MS systems to guarantee purity and trace metal compliance.
Our manufacturing processes align with REACH requirements and EDQM guidelines, ensuring smooth regulatory pathways for our clients.
We offer flexible customization options, adjusting parameters such as particle size, density, and hydration state to match client needs.
Our partnerships with reliable logistics networks help ensure stable product supply and consistent lead times for our European partners.
All operations are managed under verified quality management systems, ensuring traceability from raw materials to final delivery.
Our experienced scientific team assists clients with regulatory filings, stability studies, and process integration questions.
The production of high-value bile acids like Ursodeoxycholic Acid (UDCA) is typically achieved via two main routes:
To meet the requirements of the European Pharmacopoeia (Ph. Eur.), our bile acid products are monitored for several key parameters:
A step-by-step workflow designed to deliver custom specifications with reliable quality.
Discuss purity, particle size, and regulatory needs.
Deliver technical specifications and competitive pricing.
Establish terms, quality agreements, and timelines.
Provide pilot samples and CoAs for lab evaluation.
Initiate scale-up under monitored manufacturing conditions.
Run quality control testing and compile regulatory files.
Coordinate logistics and customs clearance for French ports.
Operating under recognized quality systems, including ISO9001, ISO22000, HALAL, KOSHER, and FDA registrations.
Sharing our latest research findings and updates from key industry exhibitions.
An analysis of supply trends and pricing in the bioactives market, highlighting how changing material costs influence downstream synthesis workflows.
Chenlv Herb invites industry partners to discuss trends in botanical extraction and chemical synthesis, exploring new technologies at CPHI China.
Our team presents new developments in chemical purification and enzyme-catalyzed transformations at the API conference in Guangzhou.
Detailed answers to common technical, regulatory, and logistics questions from procurement and R&D teams.
High-purity chemical intermediates and active components for research and manufacturing in France.
Chenlv Herb
